Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
| Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | NCI_REELIN SIGNALING PATHWAY |
| Enrichment Score (ES) | -0.8052705 |
| Normalized Enrichment Score (NES) | -1.762503 |
| Nominal p-value | 0.0 |
| FDR q-value | 0.031269778 |
| FWER p-Value | 0.079 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | RELN | 6510037 | 5274 | 0.206 | -0.2774 | No | ||
| 2 | VLDLR | 870722 3060047 5340452 6550131 | 5710 | 0.161 | -0.2960 | No | ||
| 3 | MAP2K7 | 2260086 | 6441 | 0.111 | -0.3319 | No | ||
| 4 | GRIN2A | 6550538 | 6647 | 0.101 | -0.3398 | No | ||
| 5 | DAB1 | 2060193 7000605 | 7071 | 0.083 | -0.3601 | No | ||
| 6 | PIK3R1 | 4730671 | 7309 | 0.074 | -0.3706 | No | ||
| 7 | PAFAH1B1 | 4230333 6420121 6450066 | 8122 | 0.051 | -0.4127 | No | ||
| 8 | AKT1 | 5290746 | 9328 | 0.027 | -0.4767 | No | ||
| 9 | RAP1A | 1090025 | 11113 | -0.003 | -0.5726 | No | ||
| 10 | GRIN2B | 3800333 | 11885 | -0.018 | -0.6135 | No | ||
| 11 | RAPGEF1 | 60040 4590670 | 12555 | -0.033 | -0.6485 | No | ||
| 12 | MAPT | 360706 1230706 | 13214 | -0.056 | -0.6822 | No | ||
| 13 | ARHGEF2 | 3360577 | 13370 | -0.064 | -0.6886 | No | ||
| 14 | PIK3CA | 6220129 | 13874 | -0.096 | -0.7128 | No | ||
| 15 | LRP8 | 3610746 5360035 | 14182 | -0.127 | -0.7254 | No | ||
| 16 | ITGA3 | 4570427 | 15252 | -0.404 | -0.7707 | No | ||
| 17 | FYN | 2100468 4760520 4850687 | 15896 | -0.745 | -0.7827 | Yes | ||
| 18 | NCK2 | 2510010 | 15978 | -0.794 | -0.7630 | Yes | ||
| 19 | ITGB1 | 5080156 6270528 | 16632 | -1.320 | -0.7582 | Yes | ||
| 20 | MAPK8 | 2640195 | 16851 | -1.569 | -0.7223 | Yes | ||
| 21 | LRPAP1 | 5570253 | 17074 | -1.812 | -0.6794 | Yes | ||
| 22 | MAP3K11 | 7000039 | 17284 | -2.094 | -0.6272 | Yes | ||
| 23 | CDK5 | 940348 | 17457 | -2.346 | -0.5653 | Yes | ||
| 24 | GSK3B | 5360348 | 18027 | -3.582 | -0.4874 | Yes | ||
| 25 | CBL | 6380068 | 18068 | -3.711 | -0.3771 | Yes | ||
| 26 | CRKL | 4050427 | 18419 | -5.557 | -0.2275 | Yes | ||
| 27 | CDK5R1 | 3870161 | 18581 | -7.857 | 0.0019 | Yes |
